Publications
A list of all our publications and preprints.
Multiscale analysis and functional validation of the cellular and genetic determinants of skeletal disease
Musculoskeletal diseases are a major health burden. Development of bone-active therapies has been hindered by limited understanding of the cells and genes that regulate the skeleton...
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Dissecting the genetic architecture of knee alignment reveals its contribution to osteoarthritis risk [PREPRINT]
To investigate the biological and clinical relevance of knee alignment in osteoarthritis by integrating population-scale imaging, genome-wide association, and functional genetic analyses...
Read Full ArticleThe genetic architecture of trabecular bone score and association with fracture: a genome-wide association and meta-analysis [PREPRINT]
Trabecular bone score (TBS) is a texture-based measurement derived from DXA scans, which describes the distribution of mineral across...
Read Full ArticleMultiscale analysis and functional validation of the cellular and genetic determinants of skeletal disease [PREPRINT]
Musculoskeletal diseases are a major global health burden. Development of new bone-active therapies is hindered by limited understanding of the complex interactions...
Read Full Article